Diane received her Ph.D. in the history of art from the University of Pennsylvania. After teaching 20th-century art history at Temple University she became the curator of the "Ars Medica" collection of the Philadelphia Museum of Art where she was responsible for acquiring, researching, and developing Art, Medicine and the Human Condition, an exhibition that traveled to 20 countries after opening at the PMA. She collaborated with Dan Fox on In Time of Plague, an exhibition at the American Museum of Natural History in New York. Diane moved to New York to become the director of New Observations Magazine, an artist-based contemporary arts journal dedicated to presenting a diversity of editorial voices and images to represent the diversity of the arts community. In September 2001 she moved to Santa Fe, New Mexico, to become the director of the Santa Fe Art Institute.

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